Welcome Welcome Welcome Welcome Welcome
Welcome Welcome Welcome Welcome Welcome
Advanced Search  

Tuesday, July 07th, 2020  
What's New
Mailing List

Refractometer MASTER-SUR/NM

The MASTER-SUR/NM is designed for clinical purposes: "Serum Protein", "Specific Gravity of Urine" and "Refractive Index". The plastic body model is designed to be resistant salty and acidic samples. The MASTER-SUR/NM is a good alternative choice when the water resistant feature is not a priority and the Temperature ... more

 ESCO Class II Safety Cabinet
Home : Our Principals : ESCO : Biotechnology Equipment ESCO : ESCO Class II Safety Cabinet

Airstream® Class II Biohazard Safety Cabinets E series and S series

The Esco Airstream® E and S-series Class II Biohazard Safety Cabinets are the latest generation of the original Esco Class II Biohazard Safety Cabinet product, offering a sensible balance of quality, performance features and cost-effectiveness.

These models are suitable for use with agents assigned to biosafety levels 1, 2 and 3 (in particular 2 and 3) and provide unparalleled protection for the operator and the environment from biological hazards, in addition to an unequalled level of protection for the product from external airborne contamination and cross contamination.

Drawing from a dialogue of over 20 years with our users, Esco engineers have re-designed every component for better performance, longer durability and easier use. Advanced airflow visualization has been employed during type-testing in our laboratories to ensure maximum containment for improved operator protection, and better airflow uniformity within the work zone for better product protection.

The industry-exclusive features designed into this cabinet include a world first (patent pending) backward curve motorized impeller (replaces conventional blowers) positive plenum design. While the technology employed is state-of-the-art, the results obtained are simple to appreciate: better airflow uniformity for enhanced product protection, improved energy efficiency for lower operating costs, and a more comfortable working environment as a result of reduced noise and vibration levels.

Another key innovation for which Esco is now recognised for - our use of mini-pleat ULPA (Ultra Low Penetration Air) filter technology as opposed to conventional HEPA filters - is especially pertinent to the applications for which these cabinets have been designed for. Operating at typical efficiencies of 99.9998% at MPPS (Most Penetrating Particle Size) and 99.9999% at 0.3 and 0.12 microns (compared with typical HEPA filters which are 99.99% efficient at 0.3 microns), ULPA filtration technology on these cabinets provides a higher level of operator, product and cross contamination protection.

The Esco Airstream® Class II Biohazard Safety Cabinets are now available in two versions : E-series (with transparent glass side walls) and S-series (with stainless steel interior).

The Esco Airstream® Class II Biohazard Safety Cabinet has been independently certified and type-tested by Health Protection Agency (HPA, formerly CAMR, the Centre for Applied Microbiological Research, Porton Down, Salisbury, UK) for compliance with the Class II requirements of the EN12469:2000 (European standard for microbiological safety cabinets). The type-testing performed included stringent evaluations of cabinet airflows, containment, and operator comfort factors.

Class II cabinets provide product, operator and environment protection. They are suitable for general microbiological work with agents assigned to biosafety levels 1, 2, or 3. Class II cabinets are recommended for most applications and are the most common and cost-effective systems available on the market today.

The inflow moves from the room into perforations located towards the front of the work zone (in order to prevent contamination of the product, the inflow does not mix with the clean air present in the actual work zone of the cabinet), and then travels through an air return path below the work surface.

An ULPA-filtered vertical laminar flow air stream within the cabinet (also referred to as the downflow - large light blue arrows on the airflow diagram) moves downwards from the top of the work zone towards the work surface. A filter mounted in the ceiling of the working area provides this airflow and ensure the work zone is continuously "bathed" in clean air, therefore protecting the product / samples in the work zone from contamination present in normal room air.

The downflow is uniform - all velocity readings are within +/-20% of the average velocity. The uniform nature of the air stream ensures a high level of protection against cross-contamination between various samples placed at different locations within the cabinet work zone.

Close to the work surface, the downflow air stream splits with a portion moving forward and entering the front air grille, and the remainder moving backward towards the back air grille. With the inflow, air is moved within the cabinet, through an air return path (underneath the work surface, and behind the back wall) to a plenum in which the blower system is mounted.

For the S-series: In addition, a small portion of the filtered downflow air enters the airflow intake perforations referred to as side capture zones at the front of the side walls at high velocities (indicated on the diagram with small blue arrows). This forms an air barrier that ensures no contaminated air enters the actual work zone, and also prevents any contamination from escaping the cabinet.

From the common air plenum, approximately 35% of the air is ULPA-filtered and exhausted (thus protecting the operator and the environment from exposure to biological hazards), while approximately 65% is ULPA-filtered and recirculated into the work zone as downflow.

When remotely exhausted to the external atmosphere via a non-airtight thimble* connection (optional), the cabinet provides protection for the operator from volatile toxic chemicals used in trace amounts, which normally would not be removed by the exhaust ULPA filter.

Main Filtration Agents

  • Two high-quality U15 ULPA filters with the typical efficiency of 99.9998% at MPPS and 99.9999% at both 0.3 and 0.12 microns provide the best product and operator protection in the world; typical filter lifespan is more than 3 years depending on ambient operating conditions and total hours in usage per day.
  • ISO Class 3 air cleanliness within work zone as per ISO 14644.1 (equivalent to Class 1 as per the US Federal Standard 209E, 100 times "cleaner" than the usual Class 100 classification on cabinets offered by the competition).
  • Mini-pleat separatorless ULPA filter technology reduces energy consumption and delivers increased laminar flow uniformity for better product / cross contamination protection; less bulky filters are also easier to handle.
  • Integral filter metal guard on ULPA filter prevents accidental damage to filter media; seamless filter gasket is permanently moulded on the filter frame and will not deteriorate over time.
  • Removable perforated powder-coated downflow diffuser provides additional protection against filter damage; in addition to increasing downflow uniformity for better product and cross contamination protection.

Main Features

  • Designed for ergonomics: the generously sized 173 mm / 7 inch work access opening (203 mm / 8 inch from work surface) allows easy access to the interior; the width of the inflow air grille has been minimized in order to place the work zone closer to the operator.
  • A removable, rounded front armrest extends the length of the cabinet’s front edge and eliminates pressure points on the arms while maximizing cabinet containment - by increasing airflow laminarity into the plane of the work access opening.
  • Smooth, corrosion-resistant, attractive exterior is free of large protrusions and easy to clean.
  • The large, generously sized interior with more usable working space for the operator. Interior surfaces are designed to eliminate protrusions, channels, and any other dif. cult to clean areas - all joints, corners and seams are expertly sealed for maximum cleanability.
  • Built-in white 5000k fluorescent lighting offers excellent illumination throughout the work zone in order to reduce operator fatigue.
  • Front sash (sliding window) is completely frameless for maximum visibility into the work zone. An enclosure houses the sash as it is raised, thus preventing exposure to any biological hazards that may have adhered to the inside.
  • Sash is counterbalanced to allow operation with minimal physical force and effort; a gas spring counter-balancing system is employed.
  • Durable grade stainless steel work surface will never rust, chip, or generate particles.
  • Work tray(s) is (are) aesthetically designed with upward-curving back edge which makes cleaning the surface a breeze with no hard-to-clean joints.
  • Side perforation holes along the side of the work tray(s) ensure fail-safe cross-contamination prevention by eliminating the possibility of any dead-air zones within the cabinet.
  • The drain pan is generously sized to contain any liquid spills and can be easily cleaned.
  • Optional Retrofit Kits™, including accessories such as electrical outlets, service fixtures can easily be field-installed. No factory-fitting is necessary. All Retrofit Kitprovisions are pre-installed on standard models (see engineering diagram on page 4 for further information).

E-series Features

  • UV-absorbing tempered glass sides increase operator comfort and provide a high level of protection against harmful UV rays when a UV lamp is installed; glass is also stronger and more durable compared to plastic materials.
  • Standard work surface is a multi-piece work tray. Each work surface tray is fabricated from a single piece of stainless steel without any fasteners, thus eliminating difficult-to-clean joints; each set of trays has lifting provisions to facilitate easy access to the lower drain spillage trough.
  • Individual trays are also easily removable for autoclaving and / or cleaning.
  • Standard Retrofit Kit™ Electrical Provisions are provided on workzone backwall.

S-series Features

  • Interior workzone is full stainless steel, which makes the workzone easy-to-clean. In addition, stainless steel is aesthetically pleasing to the eyes.
  • Standard work surface is a single-piece work tray. Work surface is fabricated from a single piece of stainless steel without any fasteners, thus eliminating difficult-to-clean joints; work tray has lifting provisions to facilitate easy access to the lower drain spillage trough.
  • Micro-holes near the front edge of the sidewalls (behind the sliding sash) eliminate the possibility of dead-air pockets.
  • Standard Retrofit Kit™ Electrical Provisions are provided on workzone sidewalls.

Technical Data

General Specifications AC2-3XX AC2-4XX AC2-5XX AC2-6XX

External Dimensions (L x W x H)

1035 x 774 x 1360 mm (40.7" x 30.5" x 52.9")

1340 x 774 x 1360 mm (52.7" x 30.5" x 52.9")

1645 x 774 x 1360 mm (64.7" x 30.5" x 52.9")

1950 x 774 x 1360 mm (76.7" x 30.5" x 52.9")

Internal Work Zone (L x W x H)

965 x 560 x 670 mm (38.0" x 22.0" x 26.4")

1270 x 560 x 670 mm (50.0" x 22.0" x 26.4")

1575 x 560 x 670 mm (62" x 22.0" x 26.4")

1880 x 560 x 670 mm (74.0" x 22.0" x 26.4")

Standards Compliance

  • EN 12469 : 2000 type-tested (exceeds requirements for Class II microbiological safety cabinets)
  • Air cleanliness : ISO 14644.1 Class 3, IEST-G-CC1001, IEST-G-CC1002 and other equivalent requirements
  • Filter performance : IEST-RP-CC034.1, IEST-RP-CC007.1, IEST-RP-CC001.3 and EN1822
  • Electrical safety : IEC 61010-1 / EN 61010-1 / UL 3101-1 / CSA C22.2 No. 1010.1-92

Average Airflow Velocities

Inflow Initial setpoint: 0.45 m/s or 90 fpm (audible / visual alarm will activate at 0.4m/s or 80fpm)


Initial setpoint: 0.31 m/s or 61 fpm (uniformity is +/-20%)

Airflow Volumes (At Initial Airflow Velocity Setpoints)

Inflow 290 cmh / 170 cfm 375 cmh / 220 cfm 460 cmh / 270 cfm 545 cmh / 320 cfm
Downflow (70%) 560 cmh / 330 cfm 740 cmh / 440 cfm 920 cmh / 540 cfm 1100 cmh / 650 cfm

Exhaust (30%)

290 cmh / 170 cfm

375 cmh / 220 cfm

460 cmh / 270 cfm

545 cmh / 320 cfm

Cleanliness Within Working Area

ISO 14644.1 Class 3, US Federal Standard 209E Class 1 / M1.5, AS 1386 Class 1.5, JIS B9920 Class 3, BS5295 Class C, Class M10,000 as per KS 27030.1 and equivalent classes of VDI 2083 and AFNOR X44101

Downflow and Exhaust Filter Type

ULPA filter with integral metal guards and filter frame gaskets; fully compliant with EN 1822 and IEST-RP-CC001.3 requirements (each cabinet has individual downflow and exhaust filters)

Filter Efficiency Ratings

Minimum: 99.9995% at 0.3µm / 99.9994% at 0.12µm / 99.9991% at MPPS
Typical: 99.9999% at 0.3µm / 99.9999% at 0.12µm / 99.9998% at MPPS

Noise Level

Typically <60 dBA at initial blower speed setting, according to EN 12469:2000
(based on 4 feet model, subject to acoustic properties of test environment)

Light Intensity

E-Series >1200 Lux / >111 foot candles, measured at work surface level (zero background) as per NSF49 test grid


>850 Lux / >79 foot candles, measured at work surface level (zero background) as per NSF49 test grid

Main Body Construction

1.5mmt / 0.06" / 16 gauge electro-galvanized steel with white oven-baked epoxy powder-coated finish

Side Wall


E-series Colourless and transparent UV-absorbing 5mm / 0.2" tempered glass


1.2 mmt / 0.05" / 18 gauge stainless steel grade 304

Work Surface Construction

E-Series 1.2 mmt / 0.05" / 18 gauge stainless steel grade 304 with BA finish


1.5 mmt / 0.06" / 16 gauge stainless steel grade 304 with 4B finish

Maximum Power Consumption / Current

220-240VAC / 50Hz 1Ph 298W / 1.30A 312W / 1.35A 560W / 2.43A 576W / 2.50A

110-130VAC / 60Hz 1Ph

398W / 3.32A

412W / 3.43A

760W / 6.33A

776W / 6.47A

Heat Output (in British Thermal Units)


220-240VAC / 50Hz 1Ph 1017 BTU 1065 BTU 1911 BTU 1966 BTU

110-130VAC / 60Hz 1Ph

1358 BTU

1406 BTU

2594 BTU

2648 BTU

Net Weight (Approximate)

190 kgs / 418 lbs

225 kgs / 495 lbs

260 kgs / 572 lbs

310 kgs / 682 lbs

Max Shipping Weight

285 kgs / 627 lbs

320 kgs / 704 lbs

355 kgs / 781 lbs

405 kgs / 891 lbs

Max Shipping Dimensions (L x W x H)

1200 x 950 x 1880 mm (47.2" x 37.4" x 74.0")

1500 x 950 x 1880 mm (59.0" x 37.4" x 74.0")

1800 x 950 x 1880 mm (70.9" x 37.4" x 74.0")

2100 x 950 x 1880 mm (82.7" x 37.4" x 74.0")

Max Shipping Volume

2.14 cbm / 75.6 cbf

2.68 cbm / 94.6 cbf

3.21 cbm / 113.4 cbf

3.75 cbm / 132.4 cbf

NOTE: Esco Airstream® S & E-series Class II Biosafety Cabinets are also available in 2ft width (AC2-2EX or AC2-2SX) on special order. Contact us for further information.

Ordering Codes for Esco Airstream® Class II Biosafety Cabinets

Power Supply Options



3 ft model 4 ft model 5 ft model 6 ft model 3 ft model 4 ft model 5 ft model 6 ft model

220-240VAC 50HZ, 1 phase









110-130VAC 60HZ, 1 phase









220-240VAC 60HZ, 1 phase









110-130VAC 50HZ, 1 phase









100-110VAC 50HZ / 60HZ









 Printable Version (View: 5248 | Print: 939)

ESCO Labculture® Class II Type A2 Biohazard Safety Cabinet
ESCO Labculture® P-series Class II Type A2 Biosafety Cabinet
ESCO Labculture® Class II Type B2 B-Series Biosafety Cabinets

ESCO Airstream® Class II Type B2 Biosafety Cabinets
ESCO SC2® Class II Biosafety Cabinet

ESCO Animal Handling Cabinet
ESCO Class II Safety Cabinet
ESCO Class III Biohazard Safety Cabinet
ESCO Custom Product
ESCO Cytotoxic Cabinet
ESCO Ergonomic Accessories
ESCO Formalin Vaporizer
ESCO Horizontal Laminar Flow Cabinet
ESCO IVF Cabinet
ESCO PCR Cabinet
ESCO Vertical Laminar Flow Cabinet
ESCO Weighing Cabinet
Options & Accessories
Sentra Niaga Puri Indah Blok T3-10
Jakarta 11610 - Indonesia
Telp: +62 (21) 581 8000, 581 9000
Fax: +62 (21) 581 6999
Home  |  About Us  |  Products  |  Download  |  Support  |  Contact Us
   Back to top